Small Business Grants from the Department of Health and Human Services


The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.


Department of Health and Human Services
 $62,853,680,968 Department of Transportation
 $56,443,571,981 Environmental Protection Agency
 $35,751,587,496 Department of Energy
 $24,661,368,000 National Aeronautics and Space Administration
 $14,024,018,821 Department of Homeland Security
 $13,986,266,741 Department of Labor
 $10,348,285,755 Department of Defense
 $10,111,366,675 Department of the Interior
 $9,806,569,960 Department of Agriculture
 $8,296,397,040 Agency for International Development
 $7,754,781,106 Department of Commerce
 $6,871,103,950 Department of Housing and Urban Development
 $6,642,477,476 Department of State
 $6,042,666,916 Department of Justice
 $5,571,395,802 Department of Education
 $2,642,831,221 Department of the Treasury
 $1,019,380,000 Other Agencies
 $724,036,487


NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders...more
Posted On - 2024-04-02


Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
The objective of this Notice of Funding Opportunity (NOFO) is to invite new and renewal applications for the Rare Diseases Clinical Research Consortia (RDCRC) that comprise the Rare Diseases Clinical...more
Posted On - 2024-04-02


Quality Improvement Center on Helplines and Hotlines
This Notice of Funding Opportunity will establish, by cooperative agreement, a Quality Improvement Center on Helplines and Hotlines (QIC-H2). The goal of the QIC-H2 is to build national capacity for...more
Posted On - 2024-04-01




Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed)
The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center...more
Posted On - 2024-04-01


Partnerships for the Development of Tools to Advance Therapeutic Discovery for Select Antibiotic-Resistant Gram-Negative Bacteria (R01 Clinical Trial Not Allowed)
The purpose of this Notice of Funding Opportunity (NOFO) is to support milestone-driven projects focused on developing and utilizing novel predictive models, assays, tools, and/or platforms based on...more
Posted On - 2024-04-01


Immunobiology of Xenotransplantation (U19 Clinical Trial Not Allowed)
The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center...more
Posted On - 2024-04-01


Discovery of Early Type 1 Diabetes Disease Processes in the Human Pancreas [HIRN Consortium on Beta Cell Death and Survival (CBDS)] (U01 Clinical Trial Not Allowed)
This Notice of Funding Opportunity (NOFO) requests applications to explore human pancreatic tissues and the immune compartment for the discovery of specific signaling or processing pathways that may...more
Posted On - 2024-04-01




NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders...more
Posted On - 2024-04-01


Adaptation of Diabetes Control Technologies for Older Adults with T1D (R01 Clinical Trial Optional)
The main objective of this NOFO is to foster development and testing of technologies adaptable to aging-related changes in older adults (aged 65 years or older) with T1D to improve diabetes...more
Posted On - 2024-04-01









Featured Government Grant Resources


Small Business Innovation Research Phase IIB Bridge Awards

In line with this mission, the NIH has recently constituted the Small Business Innovation Research Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics Toward Commercialization Program.







Small Business Administration's Portable Assistance Program

The Small Business Administration has established the Portable Assistance Program wherein they seek to provide grants to Small Business Development Lead Centers that provide services to small businesses in an effort to increase the success of small business establishments and their viability in certain communities where economic hardship is apparent and is attributable to the impact of a major disaster.


Ganesh Natarajan is the Founder and Chairman of 5FWorld, a new platform for funding and developing start-ups, social enterprises and the skills eco-system in India. In the past two decades, he has built two of India’s high-growth software services companies – Aptech and Zensar – almost from scratch to global success.






More Federal Domestic Assistance Programs


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Edited by: Michael Saunders

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